:root{--bg:#f7f8fb;--surface:#fff;--surface-2:#0f172a08;--border:#0f172a1a;--text:#0f172a;--text-muted:#0f172aa8;--accent:#4f46e5;--shadow-soft:0 10px 30px #0f172a0f;--shadow:0 18px 70px #0f172a2e}html,body{background:var(--bg);color:var(--text);margin:0;padding:0;font-family:ui-sans-serif,system-ui,-apple-system,Segoe UI,Roboto,Helvetica,Arial;overflow-x:hidden}*{box-sizing:border-box}a{color:inherit;text-decoration:none}.min-h-screen{min-height:100dvh}.mt-10{margin-top:10px}.card{background:var(--surface);border:1px solid var(--border);box-shadow:var(--shadow-soft);border-radius:16px}.p-4,.pad-16{padding:16px}.muted{color:var(--text-muted)}.error{color:#be123c;margin-top:10px;font-size:14px}.btn{background:var(--surface);border:1px solid var(--border);cursor:pointer;white-space:nowrap;border-radius:12px;padding:10px 14px;font-size:14px}.btn:hover{border-color:#4f46e559}.btn:disabled{opacity:.6;cursor:not-allowed}.btn-primary{background:var(--accent);color:#fff;cursor:pointer;white-space:nowrap;border:1px solid #4f46e559;border-radius:12px;padding:10px 14px;font-size:14px;font-weight:700}.btn-primary:hover{filter:brightness(.98)}.btn-primary:disabled{opacity:.6;cursor:not-allowed}.input{border:1px solid var(--border);background:var(--surface);border-radius:14px;outline:none;width:100%;padding:12px 14px;font-size:14px}.input:focus{border-color:#4f46e580;box-shadow:0 0 0 4px #4f46e51f}.select{width:190px}.chip{border:1px solid var(--border);background:var(--surface-2);color:#0f172ae0;border-radius:999px;align-items:center;padding:6px 10px;font-size:12px;font-weight:650;display:inline-flex}.chip-neutral{background:var(--surface-2)}.chip-phase-1{color:#1e40aff2;background:#3b82f61f;border-color:#3b82f638}.chip-phase-2{color:#5b21b6f2;background:#8b5cf61f;border-color:#8b5cf638}.chip-phase-3{color:#065f46f2;background:#10b9811f;border-color:#10b98138}.chip-phase-4{color:#92400ef2;background:#f59e0b1f;border-color:#f59e0b38}.chip-bucket-safety{color:#9f1239f2;background:#f43f5e1f;border-color:#f43f5e38}.chip-bucket-efficacy{color:#312e81f2;background:#4f46e51f;border-color:#4f46e538}.chip-bucket-enrollment{color:#92400ef2;background:#eab30824;border-color:#eab3083d}.chip-bucket-funding{color:#9a3412f2;background:#f973161f;border-color:#f9731638}.chip-bucket-regulatory{color:#075985f2;background:#0ea5e91f;border-color:#0ea5e938}.chip-bucket-strategic{color:#86198ff2;background:#d946ef1f;border-color:#d946ef38}.chip-bucket-operational{color:#0f766efa;background:#14b8a61f;border-color:#14b8a63d}.topbar{z-index:30;background:var(--surface);border-bottom:1px solid var(--border);position:sticky;top:0}.topbar-inner{align-items:center;gap:16px;max-width:1400px;margin:0 auto;padding:14px 16px;display:flex}.topbar-left{align-items:center;gap:18px;min-width:300px;display:flex}.brand{font-size:16px;font-weight:700}.nav{flex-wrap:wrap;gap:16px;display:flex}.navlink{color:var(--text-muted);border-radius:10px;padding:6px 8px;font-size:14px}.navlink:hover{color:var(--text);background:#0f172a08}.topbar-center{flex:1;min-width:260px;max-width:560px}.topbar-right{align-items:center;gap:10px;display:flex}.page{max-width:1400px;margin:0 auto;padding:18px 16px 40px}.layout{grid-template-columns:380px 1fr;align-items:start;gap:18px;display:grid}.rail{position:relative}.rail-scroll{flex-direction:column;gap:14px;max-height:calc(100dvh - 110px);padding-right:6px;display:flex;position:sticky;top:86px;overflow-y:auto}.content{min-width:0}.results-header{justify-content:space-between;align-items:center;gap:10px;margin-bottom:12px;display:flex}.results-count{font-size:16px}.count{font-weight:750}.results-controls{align-items:center;gap:10px;display:flex}.below-actions{justify-content:flex-end;margin-top:12px;display:flex}.facet-title{color:var(--text-muted);text-transform:uppercase;letter-spacing:.06em;margin-bottom:10px;font-size:12px;font-weight:800}.facet-list{flex-direction:column;gap:8px;display:flex}.facet-item{cursor:pointer;-webkit-user-select:none;user-select:none;border-radius:12px;grid-template-columns:18px 1fr auto;align-items:start;gap:10px;padding:6px;display:grid}.facet-item:hover{background:#0f172a08}.facet-item input{margin-top:2px}.facet-label{color:#0f172aeb;min-width:0;font-size:13px;line-height:1.25}.facet-count{color:var(--text-muted);white-space:nowrap;font-size:12px}.row{cursor:pointer;-webkit-user-select:none;user-select:none;align-items:flex-start;gap:10px;display:flex}.row input{margin-top:2px}.row-main{color:#0f172aeb;font-size:13px;line-height:1.35}.row-sub{color:var(--text-muted);margin-top:4px;font-size:12px;line-height:1.25}.table-scroller{-webkit-overflow-scrolling:touch;width:100%;overflow:auto hidden}.tbl{border-collapse:separate;border-spacing:0;table-layout:fixed;width:100%;min-width:1980px;font-size:14px}.th.sel,.td.sel{width:56px}.th.trial,.td.trial{width:140px}.th.title,.td.title{width:360px}.th.phase,.td.phase{width:120px}.th.area,.td.area{width:160px}.th.cond,.td.cond,.th.intv,.td.intv{width:240px}.th.status,.td.status{width:150px}.th.bucket,.td.bucket{width:170px}.th.why,.td.why{width:520px}.th{background:var(--surface);z-index:2;text-transform:uppercase;letter-spacing:.06em;color:var(--text-muted);border-bottom:1px solid var(--border);text-align:left;padding:12px;font-size:12px;position:sticky;top:0}.td{border-bottom:1px solid var(--border);vertical-align:top;padding:12px}.tr:hover{background:#0f172a05}.link{color:var(--accent);font-weight:700}.mini{color:var(--accent);cursor:pointer;background:0 0;border:0;margin-top:6px;padding:0;font-size:12px;display:block}.mini:hover{text-decoration:underline}.t-title{color:#0f172aeb;font-weight:650;line-height:1.25}.t-sub{color:var(--text-muted);margin-top:6px;font-size:12px;line-height:1.25}.why-clamp{-webkit-line-clamp:3;color:var(--text-muted);white-space:normal;-webkit-box-orient:vertical;line-height:1.3;display:-webkit-box;overflow:hidden}.td.why{position:relative}.tooltip{background:var(--surface);border:1px solid var(--border);z-index:20;pointer-events:none;border-radius:12px;width:520px;max-width:90vw;margin-top:8px;padding:12px;position:absolute;left:0;box-shadow:0 12px 36px #0f172a24}.tooltip-title{color:var(--text-muted);text-transform:uppercase;letter-spacing:.06em;margin-bottom:6px;font-size:12px;font-weight:800}.tooltip-body{color:#0f172aeb;font-size:13px;line-height:1.45}.note{color:var(--text-muted);margin-top:10px;font-size:12px}.desktop-only{display:block}.mobile-only,.mobile-only-inline{display:none}.m-list{display:block}.m-card{background:var(--surface);border:1px solid var(--border);box-shadow:var(--shadow-soft);border-radius:16px;margin:12px 0;padding:14px}.m-head{justify-content:space-between;align-items:flex-start;gap:12px;display:flex}.m-id{min-width:0}.m-title{color:#0f172aeb;margin-top:6px;font-size:14px;font-weight:800;line-height:1.25}.m-sub{color:var(--text-muted);margin-top:6px;font-size:12px;line-height:1.2}.m-actions{flex-direction:column;align-items:flex-end;gap:10px;display:flex}.m-tags{flex-wrap:wrap;gap:8px;margin-top:12px;display:flex}.m-why{border-top:1px solid var(--border);margin-top:12px;padding-top:10px}.m-why-label{text-transform:uppercase;letter-spacing:.06em;color:var(--text-muted);font-size:12px;font-weight:900}.m-why-text{color:#0f172aeb;margin-top:6px;font-size:13px;line-height:1.45}.overlay{background:#00000038;position:fixed;inset:0;transform:translateZ(0)}.modal-wrap{z-index:60;pointer-events:none;justify-content:center;align-items:flex-start;padding:72px 18px 42px;display:flex;position:fixed;inset:0}.modal{background:var(--surface);border:1px solid var(--border);width:min(1100px,96vw);max-height:92dvh;box-shadow:var(--shadow);opacity:1;isolation:isolate;pointer-events:auto;border-radius:18px;overflow:hidden}.modal-hd{border-bottom:1px solid var(--border);background:var(--surface);justify-content:space-between;align-items:flex-start;gap:12px;padding:14px 16px;display:flex}.modal-bd{background:var(--surface);max-height:calc(92dvh - 64px);padding:16px 16px 28px;overflow:auto}.drawer-wrap{z-index:9999;isolation:isolate;position:fixed;inset:0;transform:translateZ(0)}.drawer-panel{background:var(--surface);border-left:1px solid var(--border);width:min(560px,94vw);height:100dvh;box-shadow:var(--shadow);flex-direction:column;display:flex;position:fixed;top:0;right:0;transform:translateZ(0)}.drawer-panel-left{border-left:0;border-right:1px solid var(--border);left:0;right:auto}.drawer-hd{border-bottom:1px solid var(--border);background:var(--surface);justify-content:space-between;align-items:flex-start;gap:12px;padding:14px 16px;display:flex}.drawer-bd{padding:16px;padding-bottom:calc(16px + env(safe-area-inset-bottom));background:var(--surface);-webkit-overflow-scrolling:touch;flex:1;overflow:auto}@media (max-width:920px){.layout{grid-template-columns:1fr}.rail,.desktop-only{display:none}.mobile-only{display:block}.mobile-only-inline{display:inline-flex}.topbar-inner{flex-wrap:wrap;gap:10px}.topbar-left{justify-content:space-between;width:100%;min-width:0}.topbar-center{width:100%;min-width:0;max-width:none}.topbar-right{-webkit-overflow-scrolling:touch;width:100%;padding-bottom:2px;overflow-x:auto}.topbar-right::-webkit-scrollbar{display:none}.btn,.btn-primary{padding:10px 12px}.select{width:160px}.results-header{flex-direction:column;align-items:flex-start;gap:10px}.results-controls,.results-controls .input.select{width:100%}.modal-wrap{padding:56px 12px 18px}}@media (max-width:520px){.drawer-panel,.drawer-panel-left{width:100vw}.modal{width:96vw;max-height:94dvh}.modal-bd{padding:14px 12px 22px}}.table-scroller{touch-action:pan-x;overscroll-behavior-x:contain;scroll-behavior:auto}.table-scroller>div{touch-action:pan-y;overscroll-behavior-y:contain;-webkit-overflow-scrolling:touch}